Natural extracts derived from marine sponge-associated bacteria with diverse nonribosomal peptide synthetase genes have anticancer activities
نویسندگان
چکیده
Assessment of cytotoxicity, antibacterial activity and phytochemical screening ethanol extract Phyllanthus acidus L. (family: Euphorbiacceae) BarkSubrata Kumar Biswas, Anusua Chowdhury, Joysree Das, Utpal Karmakar, Manik Chandra Shill, Sheikh Zahir Raihan
منابع مشابه
Biosurfactant production from marine bacteria associated with sponge Callyspongia diffusa
Marine-derived biosurfactants have gained significant attention due to their structural and functional diversity. Biosurfactant production was performed using bacteria associated with Callyspongia diffusa, a marine sponge inhabiting the southern coast of India. A total of 101 sponge-associated bacteria were isolated on different media, of which 29 isolates showed positive result for biosurfacta...
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Genomic mining revealed one major nonribosomal peptide synthetase (NRPS) phylogenetic cluster in 12 marine sponge species, one ascidian, an actinobacterial isolate and seawater. Phylogenetic analysis predicts its taxonomic affiliation to the actinomycetes and hydroxy-phenyl-glycine as a likely substrate. Additionally, a phylogenetically distinct NRPS gene cluster was discovered in the microbial...
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Despite the huge investment into research and the significant effort and advances made in the search for new anticancer drugs in recent decades, cancer cure and treatment continue to be a formidable challenge. Many sources, including plants, animals, and minerals, have been explored in the oncological field because of the possibility of identifying novel molecular therapeutics. Marine sponges a...
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A growing body of evidence indicates that marine sponge-derived microbes possess the potential ability to make prolific natural products with therapeutic effects. This review for the first time provides a comprehensive overview of new cytotoxic agents from these marine microbes over the last 62 years from 1955 to 2016, which are assorted into seven types: terpenes, alkaloids, peptides, aromatic...
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Secondary metabolites of the marine sponges Acanthella elongata, Axinella donnani, Callyspongia diffusa, Callyspongia subarmigera, and Echinodictyum gorgonoides were collected from fishing nets and their in vitro antibacterial properties against eight virulent marine fish pathogens were studied at incubation temperatures of 20°C and 30°C. Crude methanol extracts of the tested sponges showed spe...
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ژورنال
عنوان ژورنال: journal of applied pharmaceutical science
سال: 2022
ISSN: ['2231-3354']
DOI: https://doi.org/10.7324/japs.2022.120406